USMLE Step 1

USMLE Step 1 QUESTION of the DAY!

The diagnosis of Whipple’s disease is given to a 55 year-old man who has had diarrhea and considerable weight loss for one year. The Doctor tells him not to worry because its response to antibiotic therapy is usually prompt. What antibiotic did the Doctor prescribe?

A) Clindamycin
B) Ceftriaxone
C) Trimethoprim-sulfamethoxazole
D) Erythromycin
E) Methotrexate

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Answer: C) Trimethoprim-sulfamethoxazole is the drug of choice for Whipple’s disease. Penicillin and Tetracycline could also be used for effective treatment.


USMLE Step 1 D.O.C. of the DAY!

Drug of choice for

Actinomyces causing actinomycosis

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Penicillin G


USMLE Step 1 Fact of the DAY!

Metabolic side effects of Thiazide diuretics:

Labs that go up- G.L.U.C.
hyperglycemia
hyperlipidemia
hyperuricemia
hypercalcemia

Labs that go down- P.M.S.
Low Potassium
Low Magnesium
Low Sodium