USMLE Step 1

USMLE Step 1 QUESTION of the DAY!

2 months following her thyroidectomy, Mrs. Jones notices muscle tetany and numbness of the hands, feet, and lips. What are her laboratory tests most likely to show?

A) High serum calcium, Low serum phosphate, Low PTH
B) High serum calcium, Low serum phosphate, High PTH
C) Low serum calcium, High serum phosphate, Low PTH
D) Low serum calcium, High serum phosphate, High PTH
E) Low serum calcium, Low serum phosphate, Low PTH

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Answer: C) Low serum calcium, High serum phosphate, Low PTH. Mrs. Jones has developed hypoparathyroidism by accidental excision from her thyroid surgery. The muscle tetany and numbness is due to the severely low calcium. Serum phosphate accumulates from decreased renal excretion (no PTH).



USMLE Step 1 D.O.C. of the DAY!

Drugs of choice for

Mycobacterium tuberculosis causing tuberculosis
(4 of them)
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Pyrazinamide, Rifampin, Isoniazid, and Ethambutol


USMLE Step 1 FACT of the DAY!

Nephrotic Syndrome:
- Prolonged onset, prolonged increase in glomerular permeability to proteins, PROTEINURIA!, hypoalbuminemia leading to edema, hyperlipidemia
- Includes: membranous glomerulonephritis, minimal change disease, diabetic nephropathy, focal segmental glomerular sclerosis, SLE