USMLE Step 1 Triad of the Day!

What syndrome?
urethritis, conjunctivitis, and arthritis?

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answer: Reiter's syndrome



USMLE Step 1 Drug of the Day!

What drug has the famous side effect of Red Man syndrome?

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answer: Vancomycin


USMLE Step 1 Fact of the Day!

Cytokines, Source, Function!
IL 1 Monocytes, macrophages Stimulates T cell proliferation & IL2 produciton
IL 2 Macrophages, T & NK cells Stim prolif of B, T & NK cell
IL 3 T cells GF of tissue mast cells & hematopoietic stem cells
IL 4 T cells inc growth of B & T cells/ inc HLA II Ags
IL 5 T cells Maturation of B into plasma cell
IL 6 T cells, monocytes Maturation of B & T cell/ (-) fibroblasts
IFN alpha B cells, macrophages Antiviral activity
IFN Beta Fibroblasts Antiviral activity
IFN gamma T & NK cells Antiviral activity, (+) macrophages, inc HLA II Ags
TNF alpha Macrophages, T & NK cells T cell prolif, IL 2 prod, cytotoxicity
TNF beta T cells T cell prolif, IL 2 prod, cytotoxicity