USMLE Step 1 QUESTION of the DAY!

Hemophilia A is the most common type of hemophilia. Which of the following is a characteristic of Hemophilia A?

A) autosomal dominant
B) autosomal recessive
C) factor IX deficiency
D) bleeding time prolonged
E) aPTT prolonged

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Answer: E) aPTT prolonged. Hemophilia A is an x-linked recessive bleeding disorder. aPTT is the only screening test that is abnormal. There is a primary deficiency of Factor VIII.



USMLE Step 1 D.O.C. of the DAY!

Drug of choice for

Mycobacterium leprae causing leprosy

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Dapsone and Rifampin


USMLE Step 1 FACT of the DAY!

Parkinson’s Disease:
- onset after age 50
- decrease in Dopamine due to loss of dopaminergic substantia nigra neurons (causes depigmentation of substantia nigra)
- Lewy bodies found in damaged cells
- resting tremors, masked facies, shuffling gait, muscular rigidity
- Tx includes either increasing dopamine or decreasing acetylcholine via pharmacotherapy