USMLE Step 1 QUESTION of the DAY!

An 8 year-old boy is stung by a bee while playing in the park. Within minutes he goes into respiratory distress and unconsciousness. His reaction is mediated by:

A) complement
B) IgG antibody
C) IgM antibody
D) IgE antibody
E) Sensitized T cells

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Answer: D) IgE antibody. This child is allergic to bees. IgE antibody is the primary player responsible for an allergic reaction, Type I Hypersensitivity reaction.



USMLE Step 1 D.O.C. of the DAY!

drug of choice for

Klebsiella causing urinary tract infection

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Quinolones



USMLE Step 1 Fact of the DAY!

Rocky Mountain Spotted Fever
- caused by tick bites with intracellular obligate parasite- Rickettsia rickettsii
- organism invades capillaries causing vasculitis
- sudden fever, headache, chills, rash from extremities expanding to trunk
- leads to fulminant vasculitis, shock, thrombosis
- Dx by ELISA test
- Tx: Tetracycline