USMLE Step 1 QUESTION of the DAY!

A 42 year-old woman presents to her doctor with lymphadenopathy of the supraclavicular node and a fever. Upon biopsy of the mass there is mixed cellular infiltrate of lymphocytes, eosinophils, lacunar cells, and Reed Sternberg cells are noted. Which of the following is most likely her diagnosis?

A) Invasive lobular carcinoma of the breast
B) Non-Hodgkin Lymphoma
C) Reactive lymphadenopathy
D) Hodgkin Lymphoma
E) Polycythemia vera

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Answer: D) Hodgkin lymphoma. It is mostly a male disease except for this case which is nodular sclerosing seen in women. Reed Sternberg cells are dead give away to Hodgkin Lymphoma.


USMLE Step 1 D.O.C. of the DAY!

Drug of choice for

Haemophilus influenza causing pneumonia, meningitis

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Any 3rd generation cephalosporin i.e. ceftriaxone, cefotaxime


USMLE Step 1 Fact of the DAY!

Pheochromocytoma
- most common tumor of the Adrenal medulla
- not a common adrenal tumor
- benign and well circumscribed
- composed of chromaffin cells producing epinephrine and norepinephrine
- unilateral alone or bilateral in MEN IIA & IIB
- Symptoms: Hypertension, palpitations, tachycardia, anxiety, and excessive sweating. Death from heart failure.
- Rule of 10’s: 10% bilateral, 10% extra-adrenal, 10% malignant, 10% children, 10% familial